disease, benign essential (Vps hosting) tremor, primary cerebellar degeneration, cerebral
disease, benign essential tremor, primary cerebellar degeneration, cerebral palsy, mental retardation, organic psychosis (probable intracranial tumor) and 5 each for muscular dystrophy, pyomyositis, spina bifida occulta, alcohol dependence and cerebral malaria. The implications of the findings are important for development of community neurological services in the developing countries. Chloroquine resistance of Plasmodiurn falciparum in semi-immune children in Zaria, northern Nigeria. Lege-Oguntoye L; Abua JU; Werblinska B; Ogala WN; Slotboom AB; Olurinola PF Department of Pharmacology, Ahmadu Bello University, Zaria, Nigeria. Trans R Soc Trop Med Hyg (ENGLAND) Sep-Oct 1989, 83 (5) p599-601, Fifty-nine children with Plasmodium falciparum. malaria were subjected to the World Health Organization (WHO) extended field test to assess the in vivo sensitivity of the parasite to chloroquine in Zaria urban area, Nigeria. The parasites in 53 children (90%) were positive but those in 6 (10%) were resistant at the RI-RII level. 36 isolates from the patients were successfully cultured in vitro for the WHO standard microtest. 13 (37%) of the isolates under-went schizogony at chloroquine concentrations of 1.6 microM/litre and above. Probit analysis showed that the chloroquine concentrations producing 50% (EC50), 90% (EC90) and 99% (EC99) schizont inhibition were 0.4, 1.6 and 4.9 microM/litre, respectively. The results indicate a rapid decline in the sensitivity of P. falciparurn to chloroquine in the study area during the past 3 years. Child health and child care in Okelele: an indigenous area of the city of Ilorin, Nigeria. Adedoyin MA; Watts SJ Department of Child Health, Faculty of Health Sciences, University of Ilorin, Nigeria. Soc Sci Med (ENGLAND) 1989, 29 (12) p1333-41, ISSN 0277-9536 This paper provides a detailed analysis of the survival rates and health problems of a cohort of children born during a 5-yr period in part of the city of Ilorin, Nigera. The findings are linked to a demographic and environmental study which indicates that the study area was relatively stable in tenns of family structure and population turnover. Most people work in the informal sector, in trading, small scale crafts and service industries. At the time the survey began, in 1979, the provision of piped water supplies to the area was unreliable and sanitation provisions rudimentary. Most of the people had little or no formal education and were very poor. The study indicated that health status had improved over the 5-yr period, compared to a baseline study conducted in 1979. Common causes of child mortality and morbidity included diarrhea, acute respiratory infections, measles, and malaria. The infant mortality rate was 41.5/1000. The availability of clinic care at nominal cost, and the attendance of others at the clinic for checkups and immunization, resulted in a higher level of health for their children than otherwise would have been possible. Some problems of primary health care in the area are mentioned, in the light of Nigeria s current budgetary problems, and the utilization of existing strong social support networks to improve health care and environmental sanitation and water supply is suggested. In-vivo sensitivity of Plasmodium falciparum. to chloroquine in Zaria, Nigeria. Midala TA; Lege-Oguntoye L; Werblinska B; Bhatt GC Department of Pharmacology, Ahmadu Bello University, Zaria, Nigeria. J Trop Med Hyg (ENGLAND) Feb 1988, 91 (1) p9-11, ISSN 0022-5304 Part I-18
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