Malaria in Nigeria: a revisit. Salako LA; Ajayi (Managed web hosting)
Malaria in Nigeria: a revisit. Salako LA; Ajayi FO; Sowunmi A; Walker O Clinical Pharmacology Unit, University College Hospital, Ibadan, Nigeria. Ann Trop Med Parasitol (ENGLAND) Oct 1990, 84 (5) p435-45, ISSN The frequency of asymptornatic malaria parasitaemia was investigated in rural and urban school- children aged six to 12 years in southwestern Nigeria between January 1987 and October 1988. Asymptornatic parasitaernia was detected in the rural school-children all year round with the lowest parasite rate in January and the highest in July, corresponding to the mid-dry and wet seasons respectively. Asymptornatic parasitaemia was also common amongst urban school- children, but the frequency was lower than in the rural children. Parasite density was less than or equal to 1000 microliters-1 in 42% of parasite-positive asymptornatic children and was greater than 10,000 microliters-1 in only 20% of them. Mass treatment with chloroquine, to which the parasites were fully sensitive, was followed by the same rate of re-infection in the parasite-positive and parasite-negative groups. Of 7713 patients clinically diagnosed as having malaria 4425 were found to have parasitologically-proven malaria, and of these 4239 had pure Plasmodiurn falciparum malaria. Of the patients with falciparum. malaria only 4.6% were below the age of one year. In 47% the parasite count was less than or equal to 1000 microliters-1, and it was over 10,000 microliters-1 in 37% and over 25 0,000 microliters-1 in 16%. There was no significant difference between the asymptornatic children and the acutely ill patients in the percentage with parasite densities less than or equal to 1000 microliters-1, but the percentage with parasite densities greater than 10,000 microliters-1 was significantly greater in the acute malaria patients than in those with asymptornatic parasitaernia. Neurological disorders in Nigerian Africans: a community-based study. Osuntokun BO; Adeuja AO; Schoenberg BS; Bademosi 0; Nottidge VA; Olumide AO; Ige O; Yaria F; Bolis CL ActaNeurol Scand (DENMARK) Jan 1987, 75 (1) p13-21, ISSN 0001-6314 In a Nigerian town with a stable population of 20,000, a door-to-door survey was conducted, using a questionnaire involving a complete census and a simple neurological evaluation which had previously showed a 95% sensitivity and an 80% specificity for detecting neurological disease. Positive responders were evaluated and categorised, using agreed criteria for diagnoses. Nearly 100% cooperation was obtained. Life prevalence ratio for at least one episode of headache was 51 /1000. Crude point prevalence ratio for migrainous, headache was 5.3/100, and peak age-specific ratio was in the first decade. Prevalence ratio for epilepsy was 533/100,000 and peak age-specific prevalence ratio occurred in the 5-14 years age groups. The prevalence ratio for peripheral nerve disorders was 268/100,000, and age-specific prevalence ratio for tropical neuropathy increased with age. Prevalence ratio for stroke was rather low at 58/100,000, but was probably due to the people s attitude to the disabled elderly and high mortality of stroke which showed annual mortality rate of 70/100,000 which increased with age to 1519/100,000 per year in the eighth decade. Crude prevalence ratios (cases per 100,000) for others are 112 for neurological complications (including sciatica) of spondylosis, 15 each for poliomyelitis, motor neurone disease, development speech disorders, 10 each for syncope, hereditary neuropathies. Parkinson s Part I-17
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