Ez web hosting - diseases around human dwellings indicates an intense man-vector

diseases around human dwellings indicates an intense man-vector contact creating a high level risk to the crowded urban population. The public health implications of this urbanization/modernization problem and solutions are discussed. First record of breeding populations of Aedes albopictus in continental Africa: implications for arboviral transmission. Savage HM; Ezike VI; Nwankwo AC; Spiegel R; Miller BR Division of Vector-Borne Infectious Diseases, Centers for Disease Control, Ft. Collins, CO 80522. J Am Mosq Control Assoc (UNITED STATES) Mar 1992, 8 (1) p101-3, ISSN Eggs of Aedes albopictus were collected in oviposition cups from 3 forested areas of Delta State in south-central Nigeria during September 1991 as part of a post-yellow fever outbreak investigation. These eggs were shipped to the Centers for Disease Control in Colorado, where they were reared to the adult stage and identified. This is the first record of breeding populations of Ae. albopictus in continental Africa. Other taxa. reared from the same oviposition cups included Ae. aegypti, Ae. apicoargenteus, Ae. africanus, Ae. lilii and Ae. simpsoni subgroup. The introduction and establishment of Ae. albopictus in Africa may have important implications for transmission of indigenous arboviruses. Genetic selection of a flavivirus-refractory strain of the yellow fever mosquito Aedes aegypti. Miller BR; Mitchell CJ Medical Entomology-Ecology Branch, Centers for Disease Control, Fort Collins, Colorado. Am J Trop Med Hyg (UNITED STATES) Oct 1991, 45 (4) p399-407, ISSN Two inbred (isofemale) Aedes aegypti mosquito lines were derived that manifested a resistant or susceptible phenotype following ingestion of yellow fever virus; lack of virus movement from the midgut defined the resistant phenotype. Other flaviviruses, including dengue 1-4, Uganda S, and Zika, viruses behaved in a similar fashion in the two mosquito lines. Crosses between the two lines produced progeny that were of intermediate susceptibility, indicating codominance; F2 backcrosses to the parents yielded results consistent with a major controlling genetic locus and provide evidence of a second locus, capable of modulating the phenotype of the major gene. The rapid selection necessary to fix the susceptible and refractory phenotypes support the hypothesis of a single major controlling locus. Viral movement across the midgut is likely to be governed by a single major gene and modifying minor genes or a group of closely linked genes. These inbred mosquito lines will be useful in discovering the molecular basis for flavivirus resistance in Ae. aegypti. Aedes albopictus introduction into continental Africa, 1991. MMWR Morb Mortal Wkly Rep (UNITED STATES) Dec 6 1991, 40 (48) p836-8, From April 15 through July 20, 199 1, an epidemic of yellow fever (YF) occurred in Delta State, Nigeria. In September 199 1, as part of a follow-up investigation, mosquito oviposition cups were deployed in four rural communities with YF, all within a 24-kilometer radius of the principal town of Agbor. Based on findings from the follow-up investigation, this report documents the first record of breeding populations of Ae. albopictus–a competent YF virus vector–in continental Africa. Part I-26

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